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Hyperbaric Oxygen Therapy - Antimicrobial Mechanism And Applications

Article written by: FILIP CIRCIUMARU, Kinetoterapeut
i.php?p=13. Oxigenoterapia hiperbarica

What is hyperbaric therapy?

Hyperbaric therapy is a form of medical treatment that involves exposing the body to pure oxygen at a higher pressure than normal. There are about 45 diseases approved worldwide to be treated with hyperbaric oxygen.

What effects does oxygen therapy have on the body?

  • Decreases inflammation
  • Increases the body's oxygen saturation by 20-30%
  • Increases the body's immunity
  • Increases blood circulation and stimulates the formation of new capillaries
  • Decreases toxins in the body
  • Stimulates new blood cells production
  • Increases STEM cell production in the body by 800% after 40 treatments
  • Increases healing rate

What happens during hyperbaric therapy?

The patient enters the multiplace hyperbaric chamber - a room able to accommodate more patients. Oxygen will be delivered through a comfortable mask, allowing you to relax during the process. Once you are comfortable in the room, you will be aware that the air is pushed slowly into the room - this is called compression. You will feel pressure in your eardrums similar to that felt in an airplane. At the end of the treatment, the mask will be removed and the air inside the room is released slowly. - this is called decompression. You will not feel any pain during therapy:
  • Oxygen molecules are dissolved in plasma
  • Oxygen levels increase only slightly in hemoglobin (RBC), which already works at about 95% capacity
  • Blood flow can carry six times more oxygen than normally
  • Plasma is infused with enough oxygen to sustain life without any hemoglobin
  • This oxygen-saturated plasma moves from the circulatory system to the spaces of the tissue, deepening into areas where there is no blood flow or where blood flow is diminished or compromised and carries oxygen molecules with it. Basically, through hyperbaric therapy, more oxygen is delivered to more cells than can be provided by the circulatory system.
  • The total effect is that the body has become hyper oxygenated and thus the process is known as hyperbaric oxygenation.
i.php?p=15. Terapia cu oxigen hiperbaric

The European Commission on Hyperbaric Medicine divides the diseases intended for this therapy, depending on the effects of hyperbaric therapy, into 3 degrees, namely:
Grade 1: Strictly recommended
  • CO poisoning
  • Crushing syndrome, polytrauma
  • Prevention of dental osteoradionecrosis
  • Inflammation (cystitis, prostatitis)
  • Decompression accident
  • Gas embolism
  • Anaerobic or mixed bacterial anaerobic infections
Grade 2: recommended
  • Diabetic foot injury 
  • Skin graft and muscle-skin flap
  • Osteoradionecroza
  • Proctitis/enteritis induced by radiotherapy
  • Soft tissue damage induced by radiotherapy
  • Aseptic necrosis of the femoral head, knee, ankle
  • Sudden deafness
  • Ischemic ulcer
  • Refractory chronic osteomyelitis
  • Stage IV neuroblastoma

Grade 3: Optional
  • Post anoxic encephalopathy
  • Radionecrosis of the larynx
  • Radiation therapy-induced Central Nervous System Injury
  • Post-vascular reperfusion syndrome
  • Replanting the limbs
  • Burns > 20% of the surface and grade 2
  • Acute ischemic ophthalmic disorders
  • Skin wounds secondary to inflammatory processes
Other indications:
  • Mediastinitis post-sternotomy 
  • Fat cell disease
  • Otitis
  • Acute myocardial infarction
  • Retinitis pigmentosa
  • Stroke
  • Multiple sclerosis
  • Fetoplacental insufficiency
  • Facial paralysis (Bell)
Discover the hyperbaric medicine center opened in our clinic. Centrokinetic has the top-performing hyperbaric chamber in Bucharest, with multiple medical and anti-aging uses. The Baroks chamber has 5 seats, and operates at a constant pressure of 2.5 atmospheres, being fully automated and having protocols for each condition, and can be used individually for each patient. 
Patients who use the clinic's hyperbaric therapy services benefit from:
  • The only medically accredited hyperbaric therapy chamber in Bucharest, which operates at 2.5 atmospheres (those for aesthetic use go to 1 atmosphere and have no medical benefits).
  • A safe medical procedure, without irradiation, without pain, without other side effects. 
  • The specialized medical team consists of recovery doctors, orthopedists, rheumatologists, neurologists, and neurosurgeons, meaning a multidisciplinary team specialized in all diseases that can be treated with hyperbaric therapy. 
  • Premium conditions at a fair price. Our clinic is recognized for the conditions offered and for the care of each patient. But we do not need to pay exorbitant prices to have access to quality medical services. At Centrokinetic you can find an affordable and fair price. But note that we do not have a contract with the National Health Insurance House (we do not offer state reimbursed services)

Hyperbaric therapy in sports

In the last decade, we are seeing an increasing number of people participating in sports and recreational activities, at every age level. The number of sports and leisure injuries has also increased as a result. This has forced health professionals to seek more effective and efficient therapeutic interventions in treating such injuries. Hyperbaric oxygen therapy (HBO) helps prevent injuries, but also faster recovery of athletes, improving the short and long term prognosis. 
In the USA, to date, many professional athletics teams, including hockey (NHL), football (NFL), basketball (NBA), and football (MLS), use HBO as adjuvant therapy. 
However, to date, very little has been published on the benefits of applying hyperbaric therapy and sports injuries. Most clinical trials examining the effectiveness of HBO in treating soft tissue lesions were limited in terms of sample size and study design. Additional research should be conducted to suggest and validate the significant effects of this treatment and continue to induce its importance in sports medicine.

Hyperbaric oxygen therapy in intestinal pneumatosis

Cystoid or cystic intestinal pneumatosis (intestinal emphysema) is a symptom that can occur in many gastrointestinal diseases. Hyperbaric oxygen therapy can be a successful treatment of cystoid intestinal pneumatosis and granulomatosis with polyangiitis.

READ MORE

Hyperbaric oxygen therapy in cell damage caused by radiation in gynecological cancers

Gynecological cancers treated with a combination of external beam radiation and brachytherapy, especially cervical and vaginal cancers, can result in the apex of the vagina receiving a high dose of radiation. Hyperbaric oxygen therapy has positive effects on the radiated tissues, especially the head, neck, anus, and rectum.

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Hyperbaric oxygen therapy in post-radiotherapy CNS injury

Hyperbaric oxygen therapy involves the use of so-called levels of oxygen under pressure to increase the level of oxygen in the blood. The use of hyperbaric oxygen therapy involves oxygen treatment for soft tissue radionecrosis. Read this article and find out more.

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Hyperbaric oxygenation vs normobaric oxygenation in CO poisoning

Prolonged CO exposure is responsible for more than half of fatal poisonings and is also one of the leading causes of poisoning in Western countries. We aimed to compare the effectiveness of therapy with hyperbaric oxygen (HBO) versus normobaric oxygen (NBO) in the setting of carbon monoxide poisoning (COP).

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Hyperbaric oxygen therapy in diabetic foot

Hyperbaric oxygen therapy may be effective for Wagner's grade 3 and 4 diabetic foot ulcers and need to study the real problems with patients seeking treatment and demonstrates the need to study the real problems with patients seeking treatment. The results show that it is important to follow the treatment in order for the HBOT to be efficient.

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The role of hyperbaric oxygen therapy in sports medicine

Hyperbaric oxygen is used in sports medicine to reduce hypoxia and edema and is also effective in treating stroke injuries and acute traumatic peripheral ischemia. When used clinically, hyperbaric oxygen should be considered as an adjuvant therapy used as early as possible after the diagnosis of the lesions.

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Hyperbaric oxygen therapy in muscle injuries

Muscle stretches are the most common muscle injuries suffered during performance sports. Rapid recovery from muscle injury is crucial for elite athletes who regularly are exposed to training and increased competition. Hyperbaric oxygen therapy is a safe and effective method, being a non-invasive treatment

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Hyperbaric oxygen therapy in sports injuries

Hyperbaric therapies are methods used to treat disease or injury using pressures higher than the local atmospheric pressure inside a hyperbaric chamber. The long-term effects are neovascularization (angiogenesis in hypoxic soft tissues), osteoneogenesis, and stimulation of collagen production by fibroblasts. This is beneficial for wound healing and recovery after irradiation.

READ MORE

Hyperbaric oxygen therapy in proctitis generated by radiation

Proctitis is the inflammation of the rectal mucosa causing pain, discharge, and other unusual symptoms. Pain can occur during bowel movements, it can be acute or chronic. Symptoms may vary, but the most common is tenesmus (the feeling of needing to go to the toilet), a sensation that persists even after using the toilet. This treatment should be offered to patients who fail to recover with conventional treatments for radiation-induced proctitis.

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Hyperbaric oxygen therapy in refractory osteomyelitis

Osteomyelitis is an infection of the bone or marrow caused by bacteria or mycobacteria. Hyperbaric oxygen treatments can be considered an American Heart Association (AHA) Class II recommendation for the treatment of chronic, refractory osteomyelitis

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Hyperbaric oxygen therapy in tinnitus

Hyperbaric oxygenation allows a controlled increase in oxygen pressure in the blood. This technique can be used in cases of tinnitus and sudden deafness, when certain changes in the inner ear and brain generate a lack of oxygen and, therefore, a limited intake of energy.

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Hyperbaric oxygen therapy of ischemia and reperfusion injury

Hyperbaric oxygen therapy has been found to ameliorate the damaging effects of reperfusion by early modulation of inflammation, maintenance of metabolic function in downstream tissues, and reintroduction of oxidation scavengers.

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Hyperbaric therapy in the treatment of second degree burns

HBOT has a beneficial effect on burn wound healing by reducing edema and ensuring there is adequate oxygen in microcirculation. It may speed up epithelialization and suppress unnecessary inflammation that could negatively affect normal wound healing. With further research, HBOT may become an adjuvant therapy to surgery.

READ MORE

Hyperbaric oxygen therapy

Hyperbaric therapy is a form of medical treatment that involves exposing the body to pure oxygen at a higher pressure than normal. There are about 45 diseases approved worldwide to be treated with hyperbaric oxygen.

READ MORE

Hyperbaric oxygen therapy in the management of patients with malignant otitis externa

Malignant otitis externa is a rapidly spreading bacterial infection that is aggressive and may be fatal if left untreated. Hyperbaric oxygen therapy (HBOT) is a medical treatment in which the entire body is placed in an airtight chamber at increased atmospheric pressure and has been proven to be effective for several different medical conditions.

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Hyperbaric oxygen therapy in acute myocardial infarction

If left untreated, MI will lead to the progressive loss of viable cardiomyocytes, impaired heart function, and congestive heart failure. Oxygen cycling therapy serves as a very attractive option for the treatment of myocardial infarction, because it offers some of the greatest benefits while reducing treatment time and inconvenience to the subject.

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Hyperbaric oxygen in ischemic ulcers

The present study has demonstrated that adjunct HBOT enhances the reduction of ulcer area and depth at 4 weeks in T2DM patients with ischaemic DFUs. HBOT is known to ensure hyperoxygenation of ischaemic tissue and restoration from hypoxia. Discover the hyperbaric medicine center open in our clinic. Centrokinetic has the top-performing hyperbaric chamber in Bucharest.

READ MORE

Hyperbaric therapy in femoral condylar osteonecrosis

Osteonecrosis of the knee (ONK) is a form of aseptic necrosis resulting from ischemia to subchondral bone tissue. Typically, treatment is invasive. Hyperbaric oxygen therapy (HBOT) may provide a noninvasive alternative by improving oxygenation and reperfusion of ischemic areas. This study evaluates the efficacy of HBOT in a series of ONK patients.

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Hyperbaric therapy in femoral head necrosis

Femoral head necrosis (FHN), also called avascular necrosis, or femoral head osteonecrosis is a common multifactorial condition that affects patients of any age and can lead to substantial clinical morbidity. Hyperbaric oxygen therapy (HBO) is one of the proposed treatments. Indeed, tissue oxygen promotes angiogenesis that reduces edema. Read about the effectiveness of this treatment.

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Hyperbaric oxygen therapy in central retinal artery occlusion

Central retinal artery occlusion (CRAO) is a devastating and common eye condition. It presents a sudden, unilateral, and painless loss of vision. Even when treated promptly, an acute obstruction of the central retinal artery usually leads to severe and permanent loss of vision.

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Hyperbaric therapy in irradiated maxillofacial dental implant

There are numerous studies reported for the effectiveness of HBO in the treatment of osteoradionecrosis of various bone tissues. In addition to its usefulness in treating osteoradionecrosis, this therapy can prevent it. It also combats the negative effect of irradiation, stimulates osseointegration, and improves the survival rate of the implant.

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Hyperbaric oxygen therapy in hear loss

The auditory function in the inner ear is maintained by the cochlea, which is known to have a high oxygen demand. Hyperbaric oxygen can increase the tension of oxygen in the perilymph and restore hearing in a significant number of patients with sudden hearing loss. Patients can be treated in a single-seater hyperbaric chamber or in a multiplace chamber.

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Hyperbaric therapy in traumatic ischemia

Limb trauma, which leads to direct tissue damage, plus local hypoxic disorders caused by the resulting edema, causes acute peripheral ischemia. Surgical treatment and hyperbaric oxygen are not concurrent treatment modalities but are best used to complement each other in order to provide the best outcome for the patient.

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Hyperbaric therapy in venous embolism

Small gas embolisms, as in this case, present serious risks, especially the complication of cerebral air embolism. To prevent neurological complications, it is necessary to urgently remove the air bubble. HBOT reduces the volume of the bubble, helps eliminate nitrogen, and improves the oxygenation of potentially hypoxic tissue. See the results of hyperbaric therapy in venous embolism.

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Hyperbaric therapy in osteoradionecrosis

Osteoradionecrosis (ORN) is a common consequence of radiation provided to cancer patients. Currently, hyperbaric oxygen therapy (HBOT) has a major role in improving wound healing in patients with ORN.

READ MORE

Hyperbaric oxygen therapy in soft tissue radionecrosis

Discover the hyperbaric medicine center open in our clinic. Centrokinetic has the top-performing hyperbaric chamber in Bucharest, with multiple medical and anti-aging uses. The Baroks chamber has 5 seats, and operates at a constant pressure of 2.5 atmospheres, being fully automated and having protocols for each condition, and can be used individually for each patient.

READ MORE