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Discover the hyperbaric medicine center opened in our clinic. Centrokinetic has the top-performing hyperbaric chamber in Bucharest, with multiple medical and anti-aging uses. The Baroks chamber has 5 seats, and operates at a constant pressure of 2.5 atmospheres, being fully automated and having protocols for each condition, and can be used individually for each patient.
Hyperbaric oxygen therapy - benefits
Patients who use the clinic's hyperbaric therapy services benefit from:
- The only medically accredited hyperbaric therapy chamber in Bucharest, which operates at 2.5 atmospheres (those for aesthetic use go to 1 atmosphere and have no medical benefits).
- A safe medical procedure, without irradiation, without pain, without other side effects.
- The specialized medical team consists of recovery doctors, orthopedists, rheumatologists, neurologists, and neurosurgeons, meaning a multidisciplinary team specialized in all diseases that can be treated with hyperbaric therapy.
- Premium conditions at a fair price. Our clinic is recognized for the conditions offered and for the care of each patient. But we do not need to pay exorbitant prices to have access to quality medical services. At Centrokinetic you can find an affordable and fair price. But note that we do not have a contract with the National Health Insurance House (we do not offer state reimbursed services)
Centrokinetic is keeping contact with prestigious clinics and universities in Belgium, the Netherlands, France, and Greece to constantly update treatments to provide patients with the best medical solutions.
What are the effects of oxygen therapy on the body?
- Decreases inflammation
- Increases the body's oxygen saturation by 20-30%
- Increases the body's immunity
- Increases blood circulation and stimulates the formation of new capillaries
- Decreases toxins in the body
- Stimulates the production of new blood cells
- Increases healing rate
The effect of HBOT on diabetic foot ulcers, Wagner classes 3 and 4, was assessed using a set of real-world retrospective data. The study reported the overall cure rate (74.2%) in the population for more than 2 million wounds.
There has been much debate in the literature about the general benefits of hyperbaric oxygen therapy (HBOT) in wound care. Many of the initial studies that led to positive results were performed in hospital settings and thus, not surprisingly, the results did not translate into an outpatient clinical reality.
When reporting rates of diabetic wound healing, studies refer to various diabetic foot conditions or diabetic foot ulcers of varying degrees Wagner. In many of these studies, when HBOT is administered, the total number of completed treatments is rarely taken into account, making the impact of therapy difficult to assess.
Materials and methods
The study began by reviewing and updating existing data on diabetes-specific wounds, the action of HBOT techniques, and the final clinical provisions of 682 outpatient wound care centers nationwide between January 1, 2014, and April 28, 2018.
The next phase of the analysis was to create an analytical subsample of diabetic wounds. All Wagner grade 3 or 4 diabetic ulcers that were located on the foot or toes were evaluated. The decision to use only wounds located on the foot and toes was made to focus the results on diabetic foot ulcers and not on a broader category of diabetic wounds located on the lower extremities (DWLE). As mentioned earlier, most initial HBOT studies were limited to wounds located under the ankle.
The final sample size included 25,562 diabetic foot ulcers. The study reports retrospective observational data on healing and amputation outcomes using a specific framework for measuring outcomes. Also, sample healing results were collected and reported. This allows clinicians to set healing rates in context with other types of wound care cases. Subsequently, the impact of HBOT-specific techniques in wound healing was established.
There are several types of wounds and sores on the legs, and diabetic patients may have ischemic wounds, venous ulcers, or traumatic wounds located somewhere on the lower extremity, which could be caused by diabetes.
During the study, a total of 2,651,878 wounds were assessed. The healing rate of diabetic foot wounds at the sample level was 74.2%.
Healing and amputation rates are reported for the complete sample of Wagner grade 3 and 4 diabetic foot ulcers in Table 2. Once wound exclusions are applied, the sample is reduced to 19,057 wounds with a cure rate of 56.04% and an amputation rate of 4.09%.
In conclusion, the overall cure rate of patients with diabetic wounds can reach 80% and is lower for Wagner classes 3 and 4, an indication of the difficulty of healing for patients with confusing comorbid conditions and emphasizes the importance of risk stratification when reporting results.
These data explain why therapeutic outcomes are so different and how therapy may lose its effectiveness in the outpatient setting when patients do not follow the full treatment regimen. The two most common reasons why patients gave up treatment is that they decided to do so for unknown reasons or were not satisfied with the progress of treatment. Patients who did not complete the treatment program did only 57% of them and discontinued treatment an average of 40 days after the first HBOT treatment.
When the two groups were not analyzed separately - those who received HBOT treatment and those who did not, a previously noted cure rate of 60.01% was observed. In other words, the study showed a 23% improvement in results when HBOT treatment is applied according to schedule and the overall treatment plan is followed.
Therefore, future research must include information on the patient's condition to fully appreciate the therapeutic benefit obtained using HBOT techniques. These data can also help determine patients to choose innovative treatments but also support medical staff to evolve and get the best results using multiple protocols and techniques simultaneously.
- Patients must complete the entire general care program in the hospital unit, because HBOT is an adjunct only if there is good care.
- When HBOT treatment is recommended, it should be followed according to the specific program.
This retrospective study suggests that HBOT may be effective for Wagner's grade 3 and 4 diabetic foot ulcers, which are difficult to cure and demonstrate the complexity of studying therapy using real-world observational data. Specifically, the results emphasize the importance of treatment adherence when analyzing the effectiveness of HBOT.
Also, methods of determining revascularization are often not a variable considered in the final analysis. Given that HBOT is approved for the treatment of diabetic foot, an extremely heterogeneous group that separates wounds by anatomical location and Wagner grade may provide different results. Variations in diabetic foot ulcer healing rates have been reported based on the medical units in which the treatment was applied, further complicating how the results are interpreted.
There have been several randomized studies that have shown improvements in the healing rate of diabetic foot ulcers. Some extremely quoted articles are described here. Löndahl et al published a randomized study of placebo techniques in 2010.
Also, several patients were cured in the present study, and the effect was improved in subgroups. This fact supports the conclusions of this study regarding the total results of the treatments received. The study was designed for 1 year and the significance was obtained at 9 months.
At the end of the 2 weeks, there was a significant reduction in the wound area in patients with HBOT, but at discharge, there was a significant improvement because both groups healed similarly. The impact of HBOT in the first 2 weeks was significant, given that both groups received intense attention and the only differentiated treatment was the use of HBOT. The only question that follows from this study is why the initially different results were lost to the end, and the discharge results were almost identical.
Interestingly, in this study, even if the size of the ulcers decreased, no complete cure was obtained at 1 year. For this reason, when studies on alternative therapies are made, the analyzed sample must provide complete results otherwise they will not be taken into account.
Not all studies have tested positive for HBOT to cure diabetic foot ulcers. As in the literature that assumes a positive impact of HBOT, publications that have not found any effect have limitations. Margolis and colleagues published a study on a large database using information collected from several units. There was an average of 29 treatments administered using HBOT, but no description of cure rates correlated with the number of treatments received. This study in a sample of 6,259 patients failed to demonstrate improved healing for nonischemic diabetic foot ulcers. An article published in 2016 that used a double-fictitious protocol for the treatment of diabetic foot ulcers and HBOT did not lead to any significant reduction in the amputation recommendation. Surprisingly, these patients did not receive any indication for amputation but were simply evaluated by a single surgeon through photographs and a database was created for this purpose. This study was carefully contradicted by many scientists who requested additional information.
The Cochrane study also failed to support HBOT techniques, but noted positive short-term but not long-term wound healing trends and recommended additional high-quality studies to be performed in the future.
The overall cure rate is reported at 75.9% and decreases to 72.3% when the data set is further modified to include diabetes. When Wagner's 3rd and 4th degree more advanced diabetic ulcerations are used as filters, the cure rate drops to 56.04%. The use of HBOT treatment brings this value up to 60.01%, but when only cases with completed HBOT treatment are evaluated, the cure rate is 75.24%.
Patients need to know what they are going to be involved in and be serious about following the program for this treatment approach to work. Finally, we need to use big data to help create care algorithms based on the complexity of the patient's clinical problems. The cost of care and recurrence rates are important so that hospitals can provide very good and effective treatment for these patients with complex problems.
This retrospective study is clinically relevant because it suggests that HBOT treatment may be effective for grade 3 and 4 Wagner's ulcers in diabetic foot that are difficult to heal and demonstrates the need to study the real problems with patients seeking treatment.
IN CASE YOU HAVEN'T ALREADY HEARD ABOUT US
Centrokinetic is the place where you will find clear answers and solutions for your motricity problems. The clinic is dedicated to osteoarticular diseases and is divided into the following specialized departments:
- Orthopedics , a department composed of an extremely experienced team of orthopedic doctors, led by Dr. Andrei Ioan Bogdan, primary care physician in orthopedics-traumatology, with surgical activity at Medlife Orthopedic Hospital, specialized in sports traumatology and ankle and foot surgery. .
- Pediatric orthopedics , where children's sports conditions are treated (ligament and meniscus injuries), spinal deformities (scoliosis, kyphosis, hyperlordosis) and those of the feet (hallux valgus, hallux rigidus, equine larynx, flat valgus, hollow foot).
- Neurology , which has an ultra-performing department, where consultations, electroencephalograms (EEG) and electromyography (EMG) are performed.
- Medical recovery for adults and children , department specialized in the recovery of performance athletes, in spinal disorders, in the recovery of children with neurological and traumatic diseases. Our experience is extremely rich, treating over 5000 performance athletes.
- Medical imaging , the clinic being equipped with ultrasound and MRI, high-performance devices dedicated to musculoskeletal disorders, and complemented by an experienced team of radiologists: Dr. Sorin Ghiea and Dr. Cosmin Pantu, specialized in musculoskeletal imaging.
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Hyperbaric oxygen therapy in diabetic foot
Hyperbaric oxygen therapy may be effective for Wagner's grade 3 and 4 diabetic foot ulcers and need to study the real problems with patients seeking treatment and demonstrates the need to study the real problems with patients seeking treatment. The results show that it is important to follow the treatment in order for the HBOT to be efficient.READ MORE
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Hyperbaric oxygen therapy in proctitis generated by radiation
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Hyperbaric oxygen therapy in tinnitus
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Hyperbaric oxygen therapy of ischemia and reperfusion injury
Hyperbaric oxygen therapy has been found to ameliorate the damaging effects of reperfusion by early modulation of inflammation, maintenance of metabolic function in downstream tissues, and reintroduction of oxidation scavengers.READ MORE
Hyperbaric therapy in the treatment of second degree burns
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Hyperbaric oxygen therapy in the management of patients with malignant otitis externa
Malignant otitis externa is a rapidly spreading bacterial infection that is aggressive and may be fatal if left untreated. Hyperbaric oxygen therapy (HBOT) is a medical treatment in which the entire body is placed in an airtight chamber at increased atmospheric pressure and has been proven to be effective for several different medical conditions.READ MORE
Hyperbaric oxygen therapy in acute myocardial infarction
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Hyperbaric oxygen in ischemic ulcers
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Hyperbaric therapy in femoral condylar osteonecrosis
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Hyperbaric therapy in femoral head necrosis
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Hyperbaric oxygen therapy in central retinal artery occlusion
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Hyperbaric therapy in irradiated maxillofacial dental implant
There are numerous studies reported for the effectiveness of HBO in the treatment of osteoradionecrosis of various bone tissues. In addition to its usefulness in treating osteoradionecrosis, this therapy can prevent it. It also combats the negative effect of irradiation, stimulates osseointegration, and improves the survival rate of the implant.READ MORE
Hyperbaric oxygen therapy in hear loss
The auditory function in the inner ear is maintained by the cochlea, which is known to have a high oxygen demand. Hyperbaric oxygen can increase the tension of oxygen in the perilymph and restore hearing in a significant number of patients with sudden hearing loss. Patients can be treated in a single-seater hyperbaric chamber or in a multiplace chamber.READ MORE
Hyperbaric therapy in traumatic ischemia
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Hyperbaric therapy in venous embolism
Small gas embolisms, as in this case, present serious risks, especially the complication of cerebral air embolism. To prevent neurological complications, it is necessary to urgently remove the air bubble. HBOT reduces the volume of the bubble, helps eliminate nitrogen, and improves the oxygenation of potentially hypoxic tissue. See the results of hyperbaric therapy in venous embolism.READ MORE
Hyperbaric oxygen therapy in soft tissue radionecrosis
Discover the hyperbaric medicine center open in our clinic. Centrokinetic has the top-performing hyperbaric chamber in Bucharest, with multiple medical and anti-aging uses. The Baroks chamber has 5 seats, and operates at a constant pressure of 2.5 atmospheres, being fully automated and having protocols for each condition, and can be used individually for each patient.READ MORE
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